Case of CML lymphoid blast crisis presenting as bilateral breast masses

Aneesha Hossain; Kanika Gupta; Andrew Mener; Imad Tabbara

doi:10.1136/bcr-2016-215825

Case of CML lymphoid blast crisis presenting as bilateral breast masses

BMJ Case Rep. 2016 Aug 10:2016:bcr2016215825. doi: 10.1136/bcr-2016-215825.

Authors

Aneesha Hossain¹, Kanika Gupta¹, Andrew Mener², Imad Tabbara²

Affiliations

¹ Department of Internal Medicine, George Washington University Hospital, Washington, District of Columbia, USA.
² Department of Hematology/Oncology, The George Washington University, Washington, District of Columbia, USA.

Abstract

A woman aged 42 years with a 1-month history of rapidly expanding bilateral breast masses presented with severe leucocytosis, anaemia, blurry vision, headaches and shortness of breath. Evaluation revealed chronic myeloid leukaemia in lymphoid blast crisis with extramedullary leukaemia involving her breasts.

2016 BMJ Publishing Group Ltd.

Publication types

Case Reports

MeSH terms

Adult
Blast Crisis / pathology*
Breast Neoplasms / etiology
Breast Neoplasms / pathology*
Female
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
Philadelphia Chromosome
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / complications
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics