Minimum information required for a DMET experiment reporting

Pharmacogenomics. 2016 Sep;17(14):1533-45. doi: 10.2217/pgs-2016-0015. Epub 2016 Aug 22.

Abstract

Aim: To provide pharmacogenomics reporting guidelines, the information and tools required for reporting to public omic databases.

Material & methods: For effective DMET data interpretation, sharing, interoperability, reproducibility and reporting, we propose the Minimum Information required for a DMET Experiment (MIDE) reporting.

Results: MIDE provides reporting guidelines and describes the information required for reporting, data storage and data sharing in the form of XML.

Conclusion: The MIDE guidelines will benefit the scientific community with pharmacogenomics experiments, including reporting pharmacogenomics data from other technology platforms, with the tools that will ease and automate the generation of such reports using the standardized MIDE XML schema, facilitating the sharing, dissemination, reanalysis of datasets through accessible and transparent pharmacogenomics data reporting.

Keywords: DMET; bioinformatics; minimum information requirement guidelines; personalized genomics; personalized medicine; pharmacogenomics; standardization.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Data Interpretation, Statistical
  • Humans
  • Information Dissemination
  • Pharmacogenetics*
  • Research Design*