Audiovestibular Function Deficits in Vestibular Schwannoma

Biomed Res Int. 2016:2016:4980562. doi: 10.1155/2016/4980562. Epub 2016 Sep 22.

Abstract

Introduction. Vestibular schwannomas (VS) are benign tumours of the vestibular nerve and can lead to hearing loss, tinnitus, vertigo, facial palsy, and brainstem compression. Audiovestibular diagnostic tests are essential for detection and treatment planning. Methods. Medline was used to perform a systematic literature review with regard to how audiovestibular test parameters correlate with symptoms, tumour size, and tumour location. Results. The auditory brainstem response can be used to diagnose retrocochlear lesions caused by VS. Since hearing loss correlates poorly with tumour size, a retrocochlear lesion is probably not the only cause for hearing loss. Also cochlear mechanisms seem to play a role. This can be revealed by abnormal otoacoustic emissions, despite normal ABR and new MRI techniques which have demonstrated endolymphatic hydrops of the inner ear. Caloric and head impulse tests show frequency specific dynamics and vestibular evoked myogenic potentials may help to identify the location of the tumour regarding the involved nerve parts. Conclusion. In order to preserve audiovestibular function in VS, it is important to stop the growth of the tumour and to avoid degenerative changes in the inner ear. A detailed neurotological workup helps to diagnose VS of all sizes and can also provide useful prognostic information.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Evoked Potentials, Auditory, Brain Stem / physiology
  • Hearing Loss / complications
  • Hearing Loss / physiopathology
  • Humans
  • Magnetic Resonance Imaging
  • Neuroma, Acoustic / physiopathology*
  • Vertigo / complications
  • Vertigo / physiopathology
  • Vestibular Function Tests
  • Vestibule, Labyrinth / physiopathology*