Abstract
Many processes lead to anemia. This review covers anemias that are less commonly encountered in the United States. These anemias include hemoglobin defects like thalassemia, bone marrow failure syndromes like aplastic anemia and pure red cell aplasia, and hemolytic processes such as paroxysmal nocturnal hemoglobinuria. The pathogenesis, diagnostic workup, and treatment of these rare anemias are reviewed.
Keywords:
Aplastic anemia; Burns; Drug induced; Paroxysmal nocturnal hemoglobinuria; Spur cell anemia; Thalassemia.
Copyright © 2016 Elsevier Inc. All rights reserved.
MeSH terms
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Anemia / etiology*
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Anemia / physiopathology*
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Anemia / therapy
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Anemia, Aplastic / drug therapy
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Anemia, Aplastic / physiopathology
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Anemia, Hemolytic / physiopathology
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Antibodies, Monoclonal, Humanized / therapeutic use
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Bone Marrow Diseases / physiopathology
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Bone Marrow Failure Disorders
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Burns / complications
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Copper / deficiency
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Drug-Related Side Effects and Adverse Reactions
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Hemoglobinuria, Paroxysmal / drug therapy
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Hemoglobinuria, Paroxysmal / physiopathology
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Humans
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Immunosuppressive Agents / therapeutic use
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Malnutrition / complications
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Red-Cell Aplasia, Pure / chemically induced
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Red-Cell Aplasia, Pure / physiopathology
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Thalassemia / physiopathology
Substances
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Antibodies, Monoclonal, Humanized
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Immunosuppressive Agents
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Copper
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eculizumab