Burn-related peripheral neuropathy: A systematic review

Burns. 2017 Jun;43(4):693-699. doi: 10.1016/j.burns.2016.08.003. Epub 2017 Mar 24.

Abstract

Peripheral neuropathy is the most frequent disabling neuromuscular complication of burns. However, the insidious and progressive onset of burn neuropathy makes it often undiagnosed or overlooked. In our study, we reviewed the current studies on the burn-related peripheral neuropathy to summarize the morbidity, mechanism, detecting method and management of peripheral neuropathy in burn patients. Of the 1533 burn patients included in our study, 98 cases (6.39%) were presented with peripheral neuropathy. Thermal and electrical burns were the most common etiologies. Surgical procedures, especially nerve decompression, showed good effect on functional recovery of both acute and delayed peripheral neuropathy in burn patients. It is noteworthy that, for early detection and prevention of peripheral neuropathy, electrodiagnostic examinations should be performed on burn patients independent of symptoms. Still, the underlying mechanisms of burn-related peripheral neuropathy remain to be clarified.

Keywords: Burn; Mechanism; Nerve decompression; Peripheral neuropathy.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Action Potentials
  • Burns / complications*
  • Complex Regional Pain Syndromes / diagnosis
  • Complex Regional Pain Syndromes / etiology*
  • Complex Regional Pain Syndromes / physiopathology
  • Complex Regional Pain Syndromes / therapy
  • Conservative Treatment
  • Decompression, Surgical / methods
  • Electromyography
  • Humans
  • Nerve Compression Syndromes / etiology*
  • Nerve Compression Syndromes / physiopathology
  • Nerve Compression Syndromes / surgery
  • Neural Conduction
  • Peripheral Nervous System Diseases / diagnosis
  • Peripheral Nervous System Diseases / etiology*
  • Peripheral Nervous System Diseases / physiopathology
  • Peripheral Nervous System Diseases / therapy