The role of myocardial viability in contemporary cardiac practice

Heart Fail Rev. 2017 Jul;22(4):401-413. doi: 10.1007/s10741-017-9626-3.

Abstract

Ischemic heart disease (IHD) remains the single most common cause of death worldwide. Ischemic cardiomyopathy is a major sequel of coronary artery disease. The economic health burden of IHD is substantial. In patients with old myocardial infarction (OMI), the extent of viable myocardium (VM) directly affects the short- and long-term outcome. There is a considerable collection of observational data showing substantial improvement in patients with significant left ventricular dysfunction when the need for revascularization is guided by preoperative assessment of viability and hibernation. However, a major challenge for present cardiovascular imaging is to identify better ways to assess viable but inadequately perfused myocardium and thus optimize selection of patients for coronary revascularization. Several non-invasive techniques have been developed to detect signs of viability. Hence, our aim is to provide the reader a state-of-the art review for the assessment of myocardial viability.

Keywords: Cardiac imaging; Ischemic cardiomyopathy; Myocardial viability.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Magnetic Resonance Imaging
  • Myocardial Ischemia / diagnostic imaging*
  • Myocardial Ischemia / physiopathology
  • Myocardial Ischemia / therapy*
  • Myocardial Revascularization
  • Myocardium / pathology*
  • Observational Studies as Topic
  • Positron-Emission Tomography
  • Randomized Controlled Trials as Topic
  • Tissue Survival
  • Tomography, Emission-Computed, Single-Photon
  • Ventricular Dysfunction, Left / diagnostic imaging*