Vulvar Neoplasms, Benign and Malignant

Jill I Allbritton

doi:10.1016/j.ogc.2017.04.002

Vulvar Neoplasms, Benign and Malignant

Obstet Gynecol Clin North Am. 2017 Sep;44(3):339-352. doi: 10.1016/j.ogc.2017.04.002.

Author

Jill I Allbritton¹

Affiliation

¹ Bethesda Dermpath Laboratory, 1730 Elton Road, Suite 11, Silver Spring, MD 20903, USA; Anne Arundel Dermatology, Towson, MD 21204, USA; Pathology, Johns Hopkins University, 4940 Bayview Medical Center, Eastern Avenue, Baltimore, MD 21224, USA. Electronic address: jilgardens@gmail.com.

PMID: 28778635
DOI: 10.1016/j.ogc.2017.04.002

Abstract

Cutaneous vulvar neoplasms are commonly encountered at gynecology visits, with 2% of women having a benign vulvar melanocytic nevus and 10% to 12% of nevi being vulvar. High-grade squamous intraepithelial lesions (vulvar intraepithelial neoplasia 2 or 3) occurs in 5 per 100,000 women, with increasing incidence in the past 30 years. The recognition of these lesions and differentiation between benign, premalignant, and malignant stages are crucial for adequate diagnosis, clinical monitoring, and treatment. The presentation, diagnosis, and management of benign and malignant vulvar proliferations are discussed with focus on practical aspects of clinical care.

Keywords: Basal cell carcinoma; Differentiated vulvar intraepithelial neoplasia (dVIN); Genital nevi; High-grade squamous intraepithelial lesion (HSIL); Melanosis; Paget disease; Squamous cell carcinoma (SCC); Vulvar melanoma.

Publication types

Review

MeSH terms

Female
Humans
Precancerous Conditions / diagnosis
Precancerous Conditions / pathology*
Vulva / pathology*
Vulvar Neoplasms / diagnosis
Vulvar Neoplasms / pathology*