Abstract
We have described a case of MEN-I in association with a benign pulmonary carcinoid tumor. Two other members of our patient's family also had MEN-I and benign carcinoid or adenomatous lung tumors. Hormonal assays of our patient's carcinoid lesion showed the production of gastrin, gastrin-releasing peptide, neurotensin, and somatostatin, but not serotonin, a hormonal profile distinct from those previously reported in carcinoid lung tumors unassociated with MEN-I.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Carcinoid Tumor / genetics*
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Carcinoid Tumor / metabolism
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Female
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Gastrin-Releasing Peptide
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Gastrins / metabolism
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Humans
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Lung Neoplasms / genetics*
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Lung Neoplasms / metabolism
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Middle Aged
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Multiple Endocrine Neoplasia / genetics*
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Neurotensin / metabolism
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Pedigree
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Peptides / metabolism
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Somatostatin / metabolism
Substances
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Gastrins
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Peptides
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Neurotensin
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Somatostatin
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Gastrin-Releasing Peptide