Cardiac Calcified Amorphous Tumors in a Patient with Hemodialysis for Diabetic Nephropathy

Intern Med. 2017 Nov 15;56(22):3057-3060. doi: 10.2169/internalmedicine.9057-17. Epub 2017 Sep 25.

Abstract

Calcified amorphous tumor (CAT) is a rare, non-neoplastic tumor involving calcium deposition in amorphous materials. Although its etiology is unknown, cases have frequently been reported in patients with hemodialysis for chronic kidney disease. We herein describe a case of cardiac CAT in a 64-year-old woman who had been on hemodialysis for diabetic nephropathy for 20 years, and the findings of the present patient, in association with the findings of previous case reports, suggest that end-stage renal disease seems to play an important role in the onset of CAT, especially in CAT formation at the mitral annulus, which appears to differ from CAT occurring at other sites.

Keywords: calcification; cardiac mass; chronic renal failure.

Publication types

  • Case Reports

MeSH terms

  • Adventitia / pathology
  • Calcinosis / etiology*
  • Calcinosis / pathology
  • Diabetic Nephropathies / complications*
  • Diabetic Nephropathies / therapy*
  • Female
  • Heart Neoplasms / etiology*
  • Heart Neoplasms / pathology
  • Humans
  • Middle Aged
  • Mitral Valve / pathology
  • Renal Dialysis / adverse effects*
  • Renal Dialysis / methods*