A case of segmental stiff skin syndrome treated with systemic losartan

Pediatr Dermatol. 2018 Jan;35(1):e66-e67. doi: 10.1111/pde.13330. Epub 2017 Nov 6.

Abstract

Stiff skin syndrome (SSS) is a rare, autosomal dominant cutaneous disorder with progressive, symmetric, sclerotic skin changes of the shoulders, hips, and thighs. In a recent publication, a distinct segmental variant of SSS was proposed. In this report we discuss the case of a boy with segmental SSS and review the current literature.

Keywords: genetic disease; genodermatoses; mechanisms.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Angiotensin II Type 1 Receptor Blockers / therapeutic use*
  • Child
  • Contracture / drug therapy*
  • Diagnosis, Differential
  • Humans
  • Losartan / therapeutic use*
  • Male
  • Skin / pathology
  • Skin Diseases, Genetic / drug therapy*

Substances

  • Angiotensin II Type 1 Receptor Blockers
  • Losartan

Supplementary concepts

  • Stiff Skin Syndrome