Cutaneous disorders characterized by elastolysis or loss of elastic tissue

J Dtsch Dermatol Ges. 2018 Feb;16(2):183-191. doi: 10.1111/ddg.13430.

Abstract

Along with collagen, elastic fibers are integral components of cutaneous connective tissue. A decrease in elastic fibers or loss thereof has been described in a number of clinically distinct skin diseases, both hereditary and acquired. In disorders associated with inflammation, elastophagocytosis is an important histological hallmark. Treatment is generally difficult.

Publication types

  • Review

MeSH terms

  • Anetoderma / diagnosis
  • Anetoderma / pathology
  • Anetoderma / therapy
  • Cutis Laxa / diagnosis
  • Cutis Laxa / pathology
  • Cutis Laxa / therapy
  • Elastic Tissue / pathology*
  • Granuloma, Giant Cell
  • Humans
  • Keratoderma, Palmoplantar / diagnosis
  • Keratoderma, Palmoplantar / pathology
  • Keratoderma, Palmoplantar / therapy
  • Lymphoma, T-Cell, Cutaneous / diagnosis
  • Lymphoma, T-Cell, Cutaneous / pathology
  • Lymphoma, T-Cell, Cutaneous / therapy
  • Pseudoxanthoma Elasticum
  • Skin / pathology*
  • Skin Diseases / diagnosis
  • Skin Diseases / pathology*
  • Skin Diseases / therapy
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy