Quantification of calcitonin gene expression at the cellular level in medullary carcinoma of the thyroid

Biol Cell. 1986;57(2):181-4. doi: 10.1111/j.1768-322x.1986.tb00474.x.

Abstract

Calcitonin mRNA was detected in human medullary carcinoma using an in situ hybridization technique. This specific and reproducible method could lead to a better functional characterization of medullary carcinoma and should allow the definition of new prognosis factors in medullary thyroid cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Calcitonin / genetics*
  • DNA / metabolism
  • Genes*
  • Humans
  • Nucleic Acid Hybridization
  • Plasmids
  • RNA, Messenger / genetics*
  • Thyroid Neoplasms / metabolism*
  • Thyroid Neoplasms / pathology
  • Transcription, Genetic*

Substances

  • RNA, Messenger
  • Calcitonin
  • DNA