Abstract
Using gene mapping, 16.3% of Polynesians were shown to have alpha thalassemia. These results are surprising since malaria is not found in Polynesia. Moreover, triplicated alpha gene rearrangements were identified in a further 7.7%, a frequency not seen in other populations.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromosome Mapping*
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DNA Restriction Enzymes
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Fetal Blood / analysis
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Genotype
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Globins / genetics*
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Humans
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Malaria / blood
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Malaria / genetics*
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Polynesia
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Thalassemia / genetics
Substances
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Globins
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DNA Restriction Enzymes