The Forgotten Ventricle? The Left Ventricle in Right-Sided Congenital Heart Disease

Circ Cardiovasc Imaging. 2018 Mar;11(3):e007410. doi: 10.1161/CIRCIMAGING.117.007410.

Abstract

The right ventricle has frequently been described as the forgotten ventricle in the circulation. However, its importance both in acquired and congenital heart disease is now unquestioned. This recognition has led to improved risk stratification and development of algorithms for intervention, which incorporate measurements of right ventricular function as key components of the assessment of many conditions. Indeed, such has been the emphasis on characterizing right ventricular dysfunction; the contribution of left ventricular dysfunction to the outcomes of diseases traditionally thought of as right sided has perhaps been underappreciated. In this review, we remind ourselves of the biventricular nature of almost all cardiovascular diseases and, in particular, how the left ventricle can both be a culprit in causation of, and a potential therapeutic target for, late morbidity and mortality in congenital heart disease.

Keywords: Fontan procedure; heart; heart ventricles; risk; tetralogy of Fallot.

Publication types

  • Review

MeSH terms

  • Echocardiography
  • Heart Defects, Congenital / diagnosis*
  • Heart Defects, Congenital / physiopathology
  • Heart Ventricles / abnormalities*
  • Heart Ventricles / diagnostic imaging
  • Heart Ventricles / physiopathology
  • Humans
  • Ventricular Function, Left / physiology*
  • Ventricular Function, Right / physiology*