Mesenchymal chondrosarcoma of the orbit: imaging features of CT and MRI

Br J Radiol. 2018 Oct;91(1090):20170579. doi: 10.1259/bjr.20170579. Epub 2018 Jul 25.

Abstract

Objective:: Mesenchymal chondrosarcoma (MCS) of the orbit is a rare and aggressive form of chondrosarcoma. The purpose of this study was to retrospectively identify the imaging features of mesenchymal chondrosarcoma of the orbit.

Methods:: This study included five patients with histologically confirmed MCS of the orbit who had undergone either CT, MRI, or both. Images were evaluated for the following: location, size, margin, CT density and presence or absence of calcification and/or ossification, MRI findings including dynamic contrast-enhancement and time-intensity curves.

Results:: CT was performed in four of the five patients, and all four (100%) demonstrated calcification and ossification of the mass. MRI was performed in all five patients. In two patients (40%), the mass demonstrated areas of hyperintensity on T1 weighted images.

Conclusion:: The presence of a well-defined, orbital mass with calcification and ossification on CT and, marked heterogenous enhancement and a rapid-washout pattern on dynamic MRI indicate a high probability of MCS of the orbit. In addition, MCS of the orbit can demonstrate areas of hyperintensity on T1 weighted images, representing bone marrow fat tissue of ossification.

Advances in knowledge:: MCS of the orbit is a highly malignant tumor, and early diagnosis by imaging is important. Radiologists should be aware of the imaging features of MCS of the orbit.

MeSH terms

  • Adolescent
  • Adult
  • Calcinosis / diagnostic imaging
  • Child
  • Chondrosarcoma, Mesenchymal / diagnostic imaging*
  • Chondrosarcoma, Mesenchymal / pathology
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging*
  • Male
  • Neoplasm Metastasis / diagnostic imaging
  • Orbital Neoplasms / diagnostic imaging*
  • Orbital Neoplasms / pathology
  • Ossification, Heterotopic / diagnostic imaging
  • Retrospective Studies
  • Tomography, X-Ray Computed*
  • Young Adult