Treatment of advanced bronchogenic carcinoma with adriamycin, 5-fluorouracil and methotrexate

Br J Dis Chest. 1977 Jul;71(3):179-82. doi: 10.1016/0007-0971(77)90108-5.

Abstract

The combination of adriamycin, 5-fluorouracil and methotrexate with folinic acid reversal was used to treat patients with advanced bronchogenic carcinoma. Twenty-one of 30 patients showed an objective response. This combination appears to produce useful remissions in patients with non-squamous lung cancer.

MeSH terms

  • Carcinoma, Bronchogenic / drug therapy*
  • Doxorubicin / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Fluorouracil / therapeutic use*
  • Humans
  • Leucovorin / therapeutic use
  • Lung Neoplasms / drug therapy*
  • Male
  • Methotrexate / therapeutic use*
  • Middle Aged
  • Remission, Spontaneous
  • Time Factors

Substances

  • Doxorubicin
  • Leucovorin
  • Fluorouracil
  • Methotrexate