Tetralogy of Fallot: Everything you wanted to know but were afraid to ask

Paediatr Anaesth. 2019 May;29(5):475-482. doi: 10.1111/pan.13569. Epub 2019 Apr 15.

Abstract

Tetralogy of Fallot (TOF) has four anatomic features: right ventricular hypertrophy (RVH), ventriculoseptal defect (VSD), overriding aorta and right ventricular outflow tract obstruction (RVOT) with an occurrence of 3.9 /10,000 births. The pathophysiologic effects in TOF are largely determined by the degree of RVOT and not the VSD. Intra-operative anesthetic management is also dependent on the degree of RVOT obstruction and influenced by the extent of surgical RVOT repair.

Keywords: cardiac; children; congenital heart disease; infants; neonates; surgery.

Publication types

  • Review

MeSH terms

  • Cardiac Surgical Procedures
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Tetralogy of Fallot / diagnosis
  • Tetralogy of Fallot / physiopathology*
  • Tetralogy of Fallot / surgery