Choroidal neovascular membrane associated with unilateral retinitis pigmentosa

Arch Soc Esp Oftalmol (Engl Ed). 2019 Sep;94(9):465-468. doi: 10.1016/j.oftal.2019.04.007. Epub 2019 May 27.
[Article in English, Spanish]

Abstract

A 67 year-old woman with diabetes mellitus type 2 no medical background of interest was attended in hospital due to visual loss of left eye of 4 months of onset. The fundus examination revealed findings corresponding to moderate non-proliferative diabetic retinopathy in the right eye and pigmented lesions similar to bone spicules and atrophy of the retinal pigment epithelium in the middle periphery and in the macular area in the left eye. The full-field electroretinogram was flat, with a slight insinuation of the b-wave in the light adaptation with a single flash of 3.0cd in the left eye. The optical coherence tomography showed the atrophic retina in all its layers, as well as intraretinal cysts and a serous neurosensory detachment of the macular retina with a lesion of high reflectivity in the left eye. Infectious and inflammatory diseases were ruled out. Three doses of intravitreal ranibizumab were administered monthly. The presence of choroidal neovascular membrane associated with unilateral retinitis pigmentosa has not been previously reported. The patient improved with intravitreal ranibizumab.

Keywords: Choroidal neovascular membrane; Intravitreal ranibizumab; Membrana neovascular coroidea; Ranibizumab intravítreo; Retinitis pigmentosa unilateral; Unilateral retinitis pigmentosa.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / administration & dosage
  • Angiogenesis Inhibitors / therapeutic use
  • Atrophy / pathology
  • Choroidal Neovascularization / diagnostic imaging
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology*
  • Diabetic Retinopathy / complications
  • Diabetic Retinopathy / diagnostic imaging
  • Electroretinography
  • Female
  • Fluorescein Angiography
  • Humans
  • Intravitreal Injections
  • Ranibizumab / administration & dosage
  • Ranibizumab / therapeutic use
  • Retinal Pigment Epithelium / pathology
  • Retinitis Pigmentosa / complications*
  • Retinitis Pigmentosa / diagnostic imaging
  • Tomography, Optical Coherence

Substances

  • Angiogenesis Inhibitors
  • Ranibizumab