Uterine sarcomas

Curr Probl Cancer. 2019 Aug;43(4):283-288. doi: 10.1016/j.currproblcancer.2019.06.001. Epub 2019 Jun 14.

Abstract

Uterine sarcomas comprise a small percentage of uterine malignancies. The most common uterine sarcoma is leiomyosarcoma (LMS). Early stage uterine LMS is curable with complete hysterectomy with removal of an intact uterus. Patients with metastatic disease may achieve tumor responses with improvements in quality of life, but long-term remissions are rare. In this review article, I outline adjuvant therapies for early stage resected uterine LMS, as well as treatment of metastatic disease.

Keywords: Chemotherapy; Endometrial stromal tumor; Radiation; Uterine carcinosarcoma; Uterine leiomyosarcoma.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Hysterectomy / methods*
  • Leiomyosarcoma / pathology
  • Leiomyosarcoma / surgery*
  • Prognosis
  • Quality of Life*
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / surgery*