Abstract
Thirty nuclear families ascertained through an alcoholic proband were studied using segregation and linkage analyses. Linkage was investigated between a putative alcoholism susceptibility (AS) gene and six blood group markers: ABO, Rhesus, Duffy, Kidd, Kell, and MNS. Evidence is presented suggestive of linkage between susceptibility to alcoholism and the MNS blood group.
MeSH terms
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ABO Blood-Group System / genetics
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Alcoholism / genetics*
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Chromosomes, Human, Pair 1
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Chromosomes, Human, Pair 18
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Chromosomes, Human, Pair 4
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Chromosomes, Human, Pair 9
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Duffy Blood-Group System / genetics
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Genetic Linkage*
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Genetic Markers
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Humans
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Kell Blood-Group System / genetics
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Kidd Blood-Group System / genetics
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MNSs Blood-Group System / genetics*
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Male
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Polymorphism, Genetic
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Rh-Hr Blood-Group System / genetics
Substances
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ABO Blood-Group System
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Duffy Blood-Group System
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Genetic Markers
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Kell Blood-Group System
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Kidd Blood-Group System
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MNSs Blood-Group System
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Rh-Hr Blood-Group System