Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain

Kumi Izawa; Ayako Kaitani; Tomoaki Ando; Akie Maehara; Masakazu Nagamine; Hiromichi Yamada; Taiki Ando; Takuma Ide; Moe Matsuzawa; Yoko Okamoto; Enzhi Yin; Saaya Fukase; Hexing Wang; Anna Kamei; Shino Uchida; Keiko Maeda; Nobuhiro Nakano; Koichiro Uchida; Naoto Tamura; Katsuhisa Ikeda; Nobuyuki Ebihara; Toshiaki Shimizu; David Voehringer; Axel Roers; Hideoki Ogawa; Ko Okumura; Jiro Kitaura

doi:10.1016/j.jid.2019.08.439

Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain

J Invest Dermatol. 2020 Mar;140(3):710-713.e3. doi: 10.1016/j.jid.2019.08.439. Epub 2019 Aug 30.

Authors

Kumi Izawa¹, Ayako Kaitani¹, Tomoaki Ando¹, Akie Maehara¹, Masakazu Nagamine¹, Hiromichi Yamada², Taiki Ando³, Takuma Ide⁴, Moe Matsuzawa⁵, Yoko Okamoto⁶, Enzhi Yin¹, Saaya Fukase⁵, Hexing Wang¹, Anna Kamei¹, Shino Uchida⁷, Keiko Maeda¹, Nobuhiro Nakano¹, Koichiro Uchida¹, Naoto Tamura³, Katsuhisa Ikeda⁴, Nobuyuki Ebihara⁵, Toshiaki Shimizu², David Voehringer⁸, Axel Roers⁹, Hideoki Ogawa¹, Ko Okumura¹, Jiro Kitaura¹⁰

Affiliations

¹ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
² Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
³ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Internal Medicine and Rheumatology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
⁴ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Otorhinolaryngology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
⁵ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Ophthalmology, Juntendo University Urayasu Hospital, Chiba, Japan.
⁶ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Pediatrics, Graduate School of Medicine, Tokyo University, Tokyo, Japan.
⁷ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Gastroenterology Immunology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
⁸ Department of Infection Biology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.
⁹ Institute for Immunology, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.
¹⁰ Atopy Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan. Electronic address: j-kitaura@juntendo.ac.jp.

PMID: 31476319
DOI: 10.1016/j.jid.2019.08.439

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Substitution / immunology
Animals
Cell Line
Ceramides / immunology
Ceramides / metabolism
Humans
Immunoglobulin Domains / genetics*
Lysine / genetics
Mast Cells
Mice
Mice, Transgenic
Passive Cutaneous Anaphylaxis / immunology*
Primary Cell Culture
Receptors, Immunologic / genetics*
Receptors, Immunologic / immunology
Receptors, Immunologic / metabolism
Sphingomyelins / immunology
Sphingomyelins / metabolism

Substances

CD300LF protein, human
CLM-1 protein, mouse
Ceramides
Receptors, Immunologic
Sphingomyelins
Lysine