Targeting the DCN1-UBC12 protein-protein interaction: novel approaches and future directions

Future Med Chem. 2019 Nov;11(22):2869-2871. doi: 10.4155/fmc-2019-0253. Epub 2019 Oct 31.

Authors

Yuan Fang¹, Bin Yu², Guochao Liao¹, Hong-Min Liu²

Affiliations

¹ Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
² School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.

PMID: 31668094
DOI: 10.4155/fmc-2019-0253

No abstract available

Keywords: DCN1 inhibitors; DCN1–UBC12 interaction; protein neddylation.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Cell Line
Humans
Intracellular Signaling Peptides and Proteins / metabolism*
Protein Interaction Maps
Protein Processing, Post-Translational
Ubiquitin-Conjugating Enzymes / metabolism*

Substances

DCUN1D1 protein, human
Intracellular Signaling Peptides and Proteins
Ubiquitin-Conjugating Enzymes
UBE2M protein, human