Olfactory Dysfunction and Chronic Rhinosinusitis

Omar G Ahmed; Nicholas R Rowan

doi:10.1016/j.iac.2019.12.013

Olfactory Dysfunction and Chronic Rhinosinusitis

Immunol Allergy Clin North Am. 2020 May;40(2):223-232. doi: 10.1016/j.iac.2019.12.013. Epub 2020 Jan 16.

Authors

Omar G Ahmed¹, Nicholas R Rowan²

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, 601 North Caroline Street, 6th floor, Suite 6164, Baltimore, MD 21287, USA.
² Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, 601 North Caroline Street, 6th floor, Suite 6164, Baltimore, MD 21287, USA. Electronic address: nrowan1@jhmi.edu.

PMID: 32278447
DOI: 10.1016/j.iac.2019.12.013

Abstract

Olfactory dysfunction (OD) is one of the cardinal symptoms of chronic rhinosinusitis (CRS), and its prevalence ranges from 60% to 80% in patients with CRS. It is much more common in CRS with nasal polyposis patients compared to CRS without nasal polyposis. Decreased olfactory function is associated with significant decreases in patient-reported quality of life (QOL), and notably, depression and the enjoyment of food. Objective measures can help detail the degree of OD, whereas subjective measures can help to determine in the impact on patient. There is variable treatment response to OD with both medical and surgical therapies.

Keywords: Chronic rhinosinusitis; Olfaction; Olfactory dysfunction; Olfactory loss.

Publication types

Review

MeSH terms

Chronic Disease
Endoscopy
Humans
Nasal Polyps / diagnosis
Nasal Polyps / epidemiology*
Nasal Polyps / therapy
Olfaction Disorders / diagnosis
Olfaction Disorders / epidemiology*
Olfaction Disorders / therapy
Olfactory Mucosa / immunology*
Prevalence
Rhinitis / diagnosis
Rhinitis / epidemiology*
Rhinitis / therapy
Risk
Sinusitis / diagnosis
Sinusitis / epidemiology*
Sinusitis / therapy
Smell
Steroids / therapeutic use

Substances

Steroids