Effects of Overweight and Obesity in Pregnancy on Health of the Offspring

Margaret L Dow; Linda M Szymanski

doi:10.1016/j.ecl.2020.02.005

Effects of Overweight and Obesity in Pregnancy on Health of the Offspring

Endocrinol Metab Clin North Am. 2020 Jun;49(2):251-263. doi: 10.1016/j.ecl.2020.02.005. Epub 2020 Apr 16.

Authors

Margaret L Dow¹, Linda M Szymanski²

Affiliations

¹ Mayo Clinic, 200 First Street Southwest, Rochester, MN 59505, USA. Electronic address: Dow.Margaret@mayo.edu.
² Mayo Clinic, 200 First Street Southwest, Rochester, MN 59505, USA.

PMID: 32418588
DOI: 10.1016/j.ecl.2020.02.005

Abstract

Overweight and obesity in pregnancy confer a wide range of risks on mother, fetus, and offspring throughout their lives. In addition to compounding many common pregnancy complications, including both iatrogenic preterm delivery and cesarean delivery, obesity is associated with multiple fetal anomalies, metabolic sequelae including diabetes and obesity, allergy and asthma, attention-deficit disorder, and likely many other challenges for the offspring. As targeted interventions are being developed, encouraging solid nutrition and exercise in women of childbearing age may stave off risks and mitigate obesity in the next generation.

Keywords: Childhood; Obesity; Offspring; Overweight; Pregnancy.

Publication types

Review

MeSH terms

Adult
Behavioral Symptoms* / etiology
Child
Congenital Abnormalities* / etiology
Female
Humans
Metabolic Diseases* / etiology
Neurodevelopmental Disorders* / etiology
Obesity, Maternal* / complications
Overweight* / complications
Pediatric Obesity* / etiology
Pregnancy
Prenatal Exposure Delayed Effects* / etiology
Stillbirth*