Abstract
An increasing number of children are diagnosed with differentiated thyroid cancer. With an excellent prognosis for the majority of pediatric patients, the goal of therapy is to optimize outcome while reducing complications. Increased knowledge of the somatic, oncogenic driver mutations provides opportunities to improve the accuracy of diagnosis, to stratify surgery, and to treat patients with morbidly invasive or refractory disease. Treatment complications can be reduced by referral to regional, high-volume pediatric thyroid centers.
Keywords:
Adolescent, Papillary; Follicular, Therapy; Pediatric, Child; Thyroid cancer; Thyroid nodule.
Copyright © 2020. Published by Elsevier Inc.
MeSH terms
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Adenocarcinoma, Follicular* / diagnosis
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Adenocarcinoma, Follicular* / etiology
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Adenocarcinoma, Follicular* / pathology
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Adenocarcinoma, Follicular* / therapy
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Adolescent
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Child
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Combined Modality Therapy
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Genetic Predisposition to Disease
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Humans
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Iodine Radioisotopes / therapeutic use
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Radiopharmaceuticals / therapeutic use
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Thyroid Cancer, Papillary* / diagnosis
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Thyroid Cancer, Papillary* / etiology
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Thyroid Cancer, Papillary* / pathology
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Thyroid Cancer, Papillary* / therapy
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Thyroid Neoplasms* / diagnosis
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Thyroid Neoplasms* / etiology
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Thyroid Neoplasms* / pathology
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Thyroid Neoplasms* / therapy
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Thyroidectomy
Substances
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Iodine Radioisotopes
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Radiopharmaceuticals
Supplementary concepts
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Thyroid cancer, follicular