Overview of primary adult retroperitoneal tumours

Luca Improta; Dimitri Tzanis; Toufik Bouhadiba; Khoubeyb Abdelhafidh; Sylvie Bonvalot

doi:10.1016/j.ejso.2020.04.054

Overview of primary adult retroperitoneal tumours

Eur J Surg Oncol. 2020 Sep;46(9):1573-1579. doi: 10.1016/j.ejso.2020.04.054. Epub 2020 May 21.

Authors

Luca Improta¹, Dimitri Tzanis², Toufik Bouhadiba³, Khoubeyb Abdelhafidh⁴, Sylvie Bonvalot⁵

Affiliations

¹ Department of General Surgery, Università Campus Bio-Medico, 200 Via Alvaro del Portillo, Rome, Italy. Electronic address: l.improta@unicampus.it.
² Department of Surgery, Institut Curie, PSL University, 26 Rue d'Ulm, Paris, France. Electronic address: dimitri.tzanis@curie.fr.
³ Department of Surgery, Institut Curie, PSL University, 26 Rue d'Ulm, Paris, France. Electronic address: mohammedtoufik.bouhadiba@curie.fr.
⁴ Department of Anesthesia, Institut Curie, PSL University, 26 Rue d'Ulm, Paris, France. Electronic address: khoubeyb.abdelhafidh@curie.fr.
⁵ Department of Surgery, Institut Curie, PSL University, 26 Rue d'Ulm, Paris, France. Electronic address: sylvie.bonvalot@curie.fr.

PMID: 32600897
DOI: 10.1016/j.ejso.2020.04.054

Abstract

In front of a primary retroperitoneal tumour, it is necessary to have in mind all possible diagnoses in order to specify the diagnostic strategy and the treatment. According to the World Health Organization (WHO) classification of tumours, mesenchymal benign and malignant tumours (including sarcomas and, currently, neurogenic tumours), parasympathetic tumours, extragonadal germ cell tumours, and lymphoid tumours have been identified. By definition, primary retroperitoneal tumours start independently from the retroperitoneal organs. Secondary lesions, carcinoma metastasis, and adenopathy are excluded from this definition, but they can also develop in the retroperitoneal space and lead to misdiagnoses. In the absence of positive tumour markers or an evocative biology, percutaneous biopsy is necessary. Pathological diagnosis is necessary to decide whether surgery must be done, its timing among the other treatments, and its extension. This paper summarizes all the diagnostic possibilities.

Keywords: Diagnosis; Retroperitoneal sarcoma; Retroperitoneal tumour; Surgery.

Publication types

Review

MeSH terms

Adult
Biopsy, Needle
Humans
Leiomyoma / diagnostic imaging
Leiomyoma / pathology
Leiomyoma / surgery
Leiomyosarcoma / diagnostic imaging
Leiomyosarcoma / pathology
Leiomyosarcoma / surgery*
Liposarcoma / diagnostic imaging
Liposarcoma / pathology
Liposarcoma / surgery*
Lymphangioma, Cystic / diagnostic imaging
Lymphangioma, Cystic / pathology
Lymphangioma, Cystic / surgery
Lymphoma / diagnostic imaging
Lymphoma / pathology
Lymphoma / surgery*
Myxoma / diagnostic imaging
Myxoma / pathology
Myxoma / surgery
Neoplasm Grading
Neoplasm Seeding
Neoplasm Staging
Neoplasms, Germ Cell and Embryonal / diagnostic imaging
Neoplasms, Germ Cell and Embryonal / pathology
Neoplasms, Germ Cell and Embryonal / surgery*
Neurilemmoma / diagnostic imaging
Neurilemmoma / pathology
Neurilemmoma / surgery
Neurofibrosarcoma / diagnostic imaging
Neurofibrosarcoma / pathology
Neurofibrosarcoma / surgery
Paraganglioma / diagnostic imaging
Paraganglioma / pathology
Paraganglioma / surgery
Preoperative Care
Retroperitoneal Neoplasms / diagnostic imaging
Retroperitoneal Neoplasms / pathology
Retroperitoneal Neoplasms / surgery*
Rhabdomyosarcoma / diagnostic imaging
Rhabdomyosarcoma / pathology
Rhabdomyosarcoma / surgery
Sarcoma / diagnostic imaging
Sarcoma / pathology
Sarcoma / surgery
Tomography, X-Ray Computed
Tumor Burden