Surgery for Locally Advanced and Oligometastatic Non-Small Cell Lung Cancer

Jenalee N Coster; Shawn S Groth

doi:10.1016/j.soc.2020.07.001

Surgery for Locally Advanced and Oligometastatic Non-Small Cell Lung Cancer

Surg Oncol Clin N Am. 2020 Oct;29(4):543-554. doi: 10.1016/j.soc.2020.07.001.

Authors

Jenalee N Coster¹, Shawn S Groth²

Affiliations

¹ Division of Thoracic Surgery, Micheal E. DeBakey Department of Surgery, Baylor College of Medicine, 7200 Cambridge St, Ste 6A. Houston, TX 77030, USA.
² Division of Thoracic Surgery, Micheal E. DeBakey Department of Surgery, Baylor College of Medicine, 7200 Cambridge St, Ste 6A. Houston, TX 77030, USA. Electronic address: Shawn.Groth@bcm.edu.

PMID: 32883457
DOI: 10.1016/j.soc.2020.07.001

Abstract

Locally advanced non-small cell lung cancer is a heterogeneous group of tumors that require multidisciplinary treatment. Although there is much debate with regard to their management, a multimodal treatment strategy for carefully selected patients that includes surgery can extend survival compared with nonoperative definitive therapy. As the role of targeted therapies and immune checkpoint inhibitors for these tumors becomes better defined, practices will continue to evolve.

Keywords: Chest wall invasion; Definitive chemoradiation; Locally advanced non–small cell lung cancer; Non–small cell lung carcinoma; Oligometastatic lung cancer; Salvage surgery; Stage IIIA N2; Superior sulcus tumors.

Publication types

Review

MeSH terms

Carcinoma, Non-Small-Cell Lung / secondary
Carcinoma, Non-Small-Cell Lung / surgery*
Humans
Lung Neoplasms / pathology
Lung Neoplasms / surgery*
Metastasectomy / methods*
Pneumonectomy / methods*