Systemic contact dermatitis induced by Rhus allergens in Korea: exercising caution in the consumption of this nutritious food

Clin Exp Dermatol. 2021 Mar;46(2):324-327. doi: 10.1111/ced.14458. Epub 2020 Nov 27.

Abstract

Systemic contact dermatitis (SCD) develops when a person who was previously sensitized to an allergen is exposed to the same allergen via the systemic route. In East Asia, the use of lacquer for polishing furniture is common and a part of the traditional culture. Contact exposure to tableware polished with Rhus lacquer may lead to sensitization. In Korea, SCD is commonly observed after systemic exposure to Rhus, a nutritious food item consumed because of the common belief of it improving the immune system. In this study, we reviewed the medical records of 21 Korean patients with SCD caused by Rhus ingestion. We found that the most significant epidemiological factor for SCD was the season of the year. Furthermore, 66.67% of the patients presented with leucocytosis and 23.81% showed increased liver enzyme levels. It is important to educate people on the risks associated with the systemic ingestion of Rhus.

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Aged
  • Allergens / immunology
  • Dermatitis, Contact / etiology*
  • Dermatitis, Toxicodendron / diagnosis*
  • Dermatitis, Toxicodendron / drug therapy
  • Dermatitis, Toxicodendron / epidemiology
  • Dermatitis, Toxicodendron / immunology
  • Diet, Vegetarian / adverse effects
  • Dietary Exposure / adverse effects*
  • Drug Therapy, Combination
  • Female
  • Histamine Antagonists / therapeutic use
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Republic of Korea
  • Retrospective Studies
  • Rhus / adverse effects*
  • Rhus / immunology
  • Seasons

Substances

  • Adrenal Cortex Hormones
  • Allergens
  • Histamine Antagonists