Alveolar rhabdomyosarcoma of urinary bladder presenting as acute leukemia: A diagnostic trap

Indian J Pathol Microbiol. 2020 Oct-Dec;63(4):623-626. doi: 10.4103/IJPM.IJPM_850_19.

Abstract

Rhabdomyosarcoma (RMS) masquerading as acute leukemia (AL) is very rare. We report a case which presented as acute leukemia subsequently diagnosed to be Alveolar RMS of Urinary Bladder. Although cases of RMS with leukemic presentation have been reported, to our knowledge this is the first case of Alveolar RMS of Urinary Bladder with leukemic picture at initial presentation. We would like to emphasize that this critical error can have serious consequences on the treatment and outcome of these patients.

Keywords: Acute leukemia; bone marrow; flow cytometry; immunohistochemistry; rhabdomyosarcoma.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Antineoplastic Agents / therapeutic use
  • Biopsy
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis
  • Male
  • Rhabdomyosarcoma, Alveolar / diagnosis*
  • Rhabdomyosarcoma, Alveolar / drug therapy
  • Urinary Bladder / pathology*
  • Young Adult

Substances

  • Antineoplastic Agents