Abstract
Autoantibodies that occur in autoimmune thyroid disease and that interact with the TSH receptor are reviewed. Current limited understanding of the nature of the TSH receptor is detailed, and available assays for the different types of antibodies are described. The incidence, clinical significance, and interactions of the various antibodies are summarized.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Autoantibodies / immunology*
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Graves Disease / genetics
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Graves Disease / immunology
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Humans
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Immunoglobulin G / immunology
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Long-Acting Thyroid Stimulator / immunology
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Receptors, Thyrotropin / immunology*
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Thyroid Diseases / immunology
Substances
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Autoantibodies
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Immunoglobulin G
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Receptors, Thyrotropin
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Long-Acting Thyroid Stimulator