Transposition of the Great Arteries, Ventricular Septal Defect, and Pulmonary Stenosis: Modified REV versus Rastelli

Pediatr Cardiol. 2021 Apr;42(4):762-767. doi: 10.1007/s00246-021-02538-9. Epub 2021 Jan 28.

Abstract

The objective of this study was to evaluate and compare the results of the modified réparation à l'ètage ventriculaire (REV) and the Rastelli operation for the treatment of transposition of the great arteries (TGA), ventricular septal defect (VSD), and pulmonary stenosis (PS). Records of 38 patients who underwent the modified REV (n = 16) or the Rastelli operation (n = 22) for the treatment of TGA, VSD, and PS between 2010 and 2019 were reviewed. The median age was 2.2 years (range 0.6-8.0 years) and the median weight was 11.3 kg (range 6.4-22.0 kg). No in-hospital death occurred and there were 4 early reoperations (two in each group). Overall survival at 10 years was 97.4% (100% in Modified REV group and 95.5% in Rastelli group, P = 0.39). Freedom from left ventricular outflow tract (LVOT) reoperation was 100% in both groups. Freedom from right ventricular outflow tract (RVOT) reoperation was 100% in Modified REV group and 75.4% in Rastelli group (P = 0.073). Event-free survival was 100% in Modified REV group and 72.0% in Rastelli group (P = 0.048). The most recent echocardiography showed that LVOT peak gradient was less than 10 mmHg in all patients. In Modified REV group, 30.8% of patients (4/13) had either RVOT obstruction (RVOT peak gradient more than 40 mmHg) or moderate or severe pulmonary insufficiency, while conduit stenosis (peak gradient more than 40 mmHg) was found in 25.0% of patients (3/12) in Rastelli group. The modified REV and the Rastelli operation provide satisfactory early results, as well as long-term survival and LVOT performance. However, the modified REV has better RVOT performance.

Keywords: Modified réparation à l’ètage ventriculaire; Pulmonary stenosis; Rastelli operation; Transposition of the great arteries; Ventricular septal defect.

MeSH terms

  • Arterial Switch Operation / methods*
  • Cardiac Surgical Procedures / methods
  • Child
  • Child, Preschool
  • Constriction, Pathologic / surgery
  • Echocardiography / methods
  • Female
  • Heart Defects, Congenital / surgery
  • Heart Septal Defects, Ventricular / mortality
  • Heart Septal Defects, Ventricular / surgery*
  • Heart Ventricles / surgery
  • Humans
  • Infant
  • Male
  • Pulmonary Valve Stenosis / mortality
  • Pulmonary Valve Stenosis / surgery*
  • Reoperation / statistics & numerical data
  • Survival Rate
  • Transposition of Great Vessels / mortality
  • Transposition of Great Vessels / surgery*