Haptoglobin groups in motor neuron disease

J Neurol Neurosurg Psychiatry. 1988 Mar;51(3):440-2. doi: 10.1136/jnnp.51.3.440.

Abstract

Haptoglobin (Hp) groups were investigated in 81 patients with motor neuron disease. A significant excess of heterozygotes was observed, accentuated among males and in the progressive spinal muscular atrophy subgroup. The results are discussed in terms of a possible influence of Hp in the immunological response.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Gene Frequency
  • Genetic Carrier Screening
  • Haptoglobins / genetics*
  • Humans
  • Male
  • Motor Neurons / physiology*
  • Neuromuscular Diseases / blood
  • Neuromuscular Diseases / genetics*

Substances

  • Haptoglobins