Identification of the novel HLA-DPA1*01:49 allele by next-generation sequencing

HLA. 2021 Sep;98(3):251-252. doi: 10.1111/tan.14255. Epub 2021 Jun 10.

Authors

Charlène Bouthemy¹, Marine Cargou², Gwendaline Guidicelli², Marylise Fort¹, Nicolas Congy-Jolivet¹

Affiliations

¹ CHU Toulouse, Laboratoire d'Immunologie, Institut Fédératif de Biologie, Hôpital Purpan, Toulouse, France.
² CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.

PMID: 33709616
DOI: 10.1111/tan.14255

Abstract

HLA-DPA1*01:49 differs from DPA1*01:03:01:04 by one nucleotide substitution in codon 119 in exon 3.

Keywords: HLA, HLA-DPA1*01:49; human leukocyte antigen; next-generation sequencing; novel allele.

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Exons / genetics
HLA-DP alpha-Chains* / genetics
High-Throughput Nucleotide Sequencing*
Humans

Substances

HLA-DP alpha-Chains
HLA-DPA1 antigen