Bilateral multifocal nodular oncocytic hyperplasia of the parotid gland: a rare entity

Pathologica. 2021 Apr;113(2):131-135. doi: 10.32074/1591-951X-140.

Abstract

Multifocal nodular oncocytic hyperplasia is an uncommon oncocytic lesion that rarely occurs in the parotid gland. Here, we report a case of a 43-years-old woman who presented with isolated gradual swelling in the 2 parotid regions. She underwent exofacial right parotidectomy. Histologic exam confirmed the diagnosis of oncocytoma arising in a background of multifocal nodular oncocytic hyperplasia with a histological variant of clear cells. Since the lesion was diagnosed as a benign lesion, surgery of the left side was not done. Our case is characterized by: early onset, the histological variant of clear cells and the presence of synchronous oncocytoma. We describe the clinical, histological and therapeutic features of this entity.

Keywords: bilateral; histology; multifocal nodular oncocytic hyperplasia; oncocytoma; parotid gland.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Oxyphilic* / diagnostic imaging
  • Adenoma, Oxyphilic* / surgery
  • Adult
  • Female
  • Humans
  • Hyperplasia / pathology
  • Parotid Gland / diagnostic imaging
  • Parotid Gland / pathology
  • Parotid Gland / surgery
  • Parotid Neoplasms* / diagnostic imaging
  • Parotid Neoplasms* / surgery
  • Salivary Gland Diseases* / pathology