XEN45 Gelstent Implantation in the Treatment of Glaucoma Secondary to Fuchs Uveitis Syndrome

Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1678-1685. doi: 10.1080/09273948.2021.1934035. Epub 2021 Jun 14.

Abstract

Purpose: Evaluation of treatment efficacy of XEN45 gelstent for glaucoma secondary to Fuchs uveitis syndrome (FUS).

Methods: This retrospective case series evaluated patients with glaucoma secondary to FUS, who underwent XEN45 implantation. Complete success was defined as IOP lowering of ≥ 20% and cutoff IOP at 18 mmHg. Success was qualified if additional glaucoma medication was necessary. Additional glaucoma surgery except for needling and open bleb revision was regarded as failure.

Results: Twelve eyes of 12 patients were included. Qualified and complete success rates were 50% after one year (n = 10). Qualified success was achieved in 66.6% of patients with 33.3% of patients achieving complete success after two years (n = 6).

Conclusions: XEN45 implantation had some success in the treatment of glaucoma secondary to FUS, but needling was frequently necessary to improve outcome.

Keywords: FUS; heterochromia iridis; minimally invasive glaucoma surgery; phacoemulsification; uveitic glaucoma.

MeSH terms

  • Glaucoma* / etiology
  • Glaucoma* / surgery
  • Humans
  • Retrospective Studies