Moderate Alcoholic Hepatitis

Clin Liver Dis. 2021 Aug;25(3):537-555. doi: 10.1016/j.cld.2021.03.001. Epub 2021 May 27.

Abstract

The natural history of moderate alcoholic hepatitis (AH) is not well known. It is a frequent disease with a probable underestimated incidence compared with its severe form. Among the different prognostic scores predicting short-term mortality in AH, MELD seems to be the most accurate. The mortality of moderate AH is 3% to 7% in the short to medium term and 13% to 20% at 1 year, mainly because of liver-related complications, including severe infections. Long-term abstinence is the main goal of the treatment. There is still need for the development of new therapies for AH, including the less severe forms.

Keywords: Abstinence; Alcoholic hepatitis; MELD; Moderate; Nonsevere; Survival.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Hepatitis, Alcoholic* / diagnosis
  • Hepatitis, Alcoholic* / epidemiology
  • Hepatitis, Alcoholic* / therapy
  • Humans
  • Incidence