Objective: The aim of the study was to ascertain the effect of nasal polyposis on cardiac functions.
Material and methods: A prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital. Thirty-one patients with chronic rhinosinusitis with nasal polyposis were enrolled and administered fluticasone furoate nasal spray for 3 weeks before randomly segregation into surgical or medical group. The treatment continued for 3 months in both groups. The SNOT-22 (Sino-Nasal Outcome Test-22) score, polyp grade, and right ventricular and pulmonary arterial functions were recorded in both groups before and after 3 months of the intervention.
Results: Both groups had significant improvement in SNOT-22 scores after 3 months of intervention. Both groups showed improvement in cardiac functions, but statistical significance was found only in subjects who underwent surgery.
Conclusion: Nasal polyp affects cardiac functions, and this needs further evaluation and research through studies on large samples.
Keywords: Nasal polyps; Right ventricular function; Sinusitis; Surgery.
© 2021 The Author(s). Published by S. Karger AG, Basel.