Abstract
Interleukins are polypeptides that act on leukocytes and other tissue targets. Interleukin-1, produced by macrophages and other cells, activates lymphocytes and also induces several components of the host's acute-phase response to infection and injury. Interleukin-2, produced by T lymphocytes, is a growth factor for helper, suppressor, and cytotoxic T lymphocytes. By several criteria, interleukins can be considered the hormones that regulate immune and inflammatory responses.
MeSH terms
-
Acquired Immunodeficiency Syndrome / therapy
-
Animals
-
Bacterial Infections / immunology
-
Bacterial Infections / physiopathology
-
Cells, Cultured
-
Humans
-
Immunologic Deficiency Syndromes / therapy
-
Immunotherapy
-
Inflammation / immunology
-
Inflammation / physiopathology
-
Interleukin-1 / analysis
-
Interleukin-1 / biosynthesis
-
Interleukin-1 / immunology
-
Interleukin-1 / physiology*
-
Interleukin-2 / administration & dosage
-
Interleukin-2 / biosynthesis
-
Interleukin-2 / immunology
-
Interleukin-2 / physiology*
-
Mice
-
Neoplasms, Experimental / therapy
-
T-Lymphocytes / immunology
-
T-Lymphocytes, Cytotoxic / immunology
Substances
-
Interleukin-1
-
Interleukin-2