Metamorphosis by ATG13 and ATG101 in human autophagy initiation

Autophagy. 2024 Apr;20(4):968-969. doi: 10.1080/15548627.2023.2230054. Epub 2023 Jul 2.

Abstract

ATG, Autophagy-related, HORMA, protein domain named after HOP1-MAD2-REV7; RB1CC1, RB1 inducible coiled-coil 1; ULK, Unc-51-like kinase.

Keywords: ATG2A; ATG9A; lipid transfer; membrane contact site; metamorphosis; super-complex.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Vesicular Transport / metabolism
  • Autophagy* / physiology
  • Autophagy-Related Proteins* / metabolism
  • Humans
  • Models, Biological
  • Vesicular Transport Proteins*

Substances

  • Autophagy-Related Proteins
  • ATG13 protein, human
  • ATG101 protein, human
  • Adaptor Proteins, Vesicular Transport
  • Vesicular Transport Proteins

Grants and funding

This work was funded by generous core funding by the Max Planck society and DFG SFB1190 (P19 to ACF).