Unraveling the complex relationship: Multiple sclerosis, urinary tract infections, and infertility

Mult Scler Relat Disord. 2024 Apr:84:105512. doi: 10.1016/j.msard.2024.105512. Epub 2024 Feb 20.

Abstract

Background: Multiple sclerosis (MS) is an immune system disorder that affects the central nervous system (CNS) and progressively damages nerve fibers and protective myelin. People with MS often experience a wide range of complications, including lower urinary tract dysfunction, urinary tract infections (UTIs) and sexual dysfunction. MS is common in young people and can lead to sexual dysfunction (SD) and infertility, which becomes more pronounced as the disease progresses.

Results: Over the past two decades, significant advances have been made in the management of MS, which may slow the progression of the disease and alter its course. However, UTI and SD remain significant challenges for these patients. Awareness of the underlying complications of MS, such as UTIs and infertility, is crucial for prevention, early detection and appropriate treatment, as there is a causal relationship between UTIs and the use of corticosteroids during an attack.

Conclusion: This article provides an overview of potential microbial pathogens that contribute to the development of MS, as well as an assessment of people with MS who report UTIs and infertility.

Keywords: Infertility; Multiple sclerosis; Sexual dysfunction; Urinary tract infections; Urogenital.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Humans
  • Infertility* / complications
  • Multiple Sclerosis* / complications
  • Multiple Sclerosis* / diagnosis
  • Urinary Tract Infections* / complications
  • Urinary Tract Infections* / diagnosis