Ankylosing spondylitis and rheumatoid arthritis in a patient with Paget's disease. Differential effects of indomethacin, D-penicillamine, or gold sodium thiomalate in the respective arthritides

Arch Intern Med. 1985 Oct;145(10):1915-7. doi: 10.1001/archinte.1985.00360100189033.

Abstract

A patient developed both ankylosing spondylitis and rheumatoid arthritis, each of which responded to D-penicillamine or gold sodium thiomalate and indomethacin, respectively. The patient was both HLA-B27 and -DR4 positive. In addition, he was found to have Paget's disease of bone, which has required no treatment.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Arthritis, Rheumatoid / complications*
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / immunology
  • Gold Sodium Thiomalate / therapeutic use*
  • HLA Antigens / analysis
  • HLA-B27 Antigen
  • HLA-DR4 Antigen
  • Histocompatibility Antigens Class II / analysis
  • Humans
  • Indomethacin / therapeutic use*
  • Male
  • Osteitis Deformans / complications*
  • Penicillamine / therapeutic use*
  • Radiography
  • Spondylitis, Ankylosing / complications*
  • Spondylitis, Ankylosing / diagnostic imaging
  • Spondylitis, Ankylosing / drug therapy
  • Spondylitis, Ankylosing / immunology

Substances

  • HLA Antigens
  • HLA-B27 Antigen
  • HLA-DR4 Antigen
  • Histocompatibility Antigens Class II
  • Gold Sodium Thiomalate
  • Penicillamine
  • Indomethacin