The Lesch-Nyhan syndrome

Annu Rev Med. 1973:24:41-60. doi: 10.1146/annurev.me.24.020173.000353.
No abstract available

Publication types

  • Review

MeSH terms

  • Allopurinol / therapeutic use
  • Animals
  • Brain / metabolism
  • Chromosome Aberrations
  • Chromosome Disorders
  • Guanine / metabolism
  • Humans
  • Hypoxanthines / urine
  • Lesch-Nyhan Syndrome* / diagnosis
  • Lesch-Nyhan Syndrome* / drug therapy
  • Lesch-Nyhan Syndrome* / genetics
  • Male
  • Metabolism, Inborn Errors
  • Pentosyltransferases / metabolism
  • Purines / metabolism
  • Rabbits
  • Rats
  • Uric Acid / urine

Substances

  • Hypoxanthines
  • Purines
  • Uric Acid
  • Guanine
  • Allopurinol
  • Pentosyltransferases