Control of pyrimidine biosynthesis in human lymphocytes. Simultaneous increase in activities of glutamine-utilizing carbamyl phosphate synthetase and aspartate transcarbamylase in phytohemagglutinin-stimulated human peripheral lymphocytes and their enzyme co-purification

J Biol Chem. 1973 Jan 25;248(2):389-92.
No abstract available

MeSH terms

  • Ammonium Sulfate
  • Aspartate Carbamoyltransferase / biosynthesis*
  • Aspartate Carbamoyltransferase / isolation & purification
  • Carbamates
  • Carbon Isotopes
  • Centrifugation, Density Gradient
  • Chromatography
  • Dactinomycin / pharmacology
  • Electrophoresis
  • Enzyme Induction
  • Glutamine
  • Humans
  • In Vitro Techniques
  • Lectins / antagonists & inhibitors
  • Lectins / pharmacology*
  • Lymphocytes / drug effects
  • Lymphocytes / enzymology
  • Lymphocytes / metabolism*
  • Molecular Weight
  • Multienzyme Complexes
  • Phosphotransferases / biosynthesis*
  • Phosphotransferases / isolation & purification
  • Puromycin / pharmacology
  • Pyrimidines / biosynthesis*

Substances

  • Carbamates
  • Carbon Isotopes
  • Lectins
  • Multienzyme Complexes
  • Pyrimidines
  • Glutamine
  • Dactinomycin
  • Puromycin
  • Aspartate Carbamoyltransferase
  • Phosphotransferases
  • Ammonium Sulfate