The Cronkhite-Canada syndrome

Postgrad Med J. 1973 Apr;49(570):268-73. doi: 10.1136/pgmj.49.570.268.

Abstract

The eighteenth patient and seventh survivor with the Cronkhite-Canada syndrome is described. A remission of 9 years followed gastrectomy and steroid therapy. Findings on seventeen other patients described in the literature are reviewed.

The histological features are discussed in detail. The jejunum, though macroscopically normal, showed oedema, increased vascularity and mucous gland secreting activity. The possible importance of this increased vascularity in the aetiology of this syndrome is discussed.

MeSH terms

  • Barium Sulfate
  • Diarrhea / complications
  • Gastrectomy
  • Gastrointestinal Neoplasms / complications*
  • Humans
  • Jejunum / pathology
  • Male
  • Middle Aged
  • Nails
  • Polyps / complications*
  • Prednisone / therapeutic use
  • Rectum / pathology
  • Remission, Spontaneous
  • Skin Diseases / complications*
  • Stomach / pathology
  • Stomach Neoplasms / complications
  • Syndrome

Substances

  • Barium Sulfate
  • Prednisone