Abstract
In 24 patients receiving neuroleptics, the 11 patients whose CSF homovanillic acid showed no tolerance to neuroleptics at 1 month had significantly more residual symptoms, extrapyramidal side effects, and history of psychiatric hospitalization in first-degree relatives.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Antipsychotic Agents / therapeutic use*
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Basal Ganglia Diseases / chemically induced
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Female
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Homovanillic Acid / cerebrospinal fluid*
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Hospitalization
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Hospitals, Psychiatric
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Humans
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Male
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Mental Disorders / genetics*
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Parkinson Disease, Secondary / chemically induced
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Phenylacetates / cerebrospinal fluid*
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Prognosis
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Psychotic Disorders / cerebrospinal fluid
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Psychotic Disorders / drug therapy*
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Psychotic Disorders / psychology
Substances
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Antipsychotic Agents
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Phenylacetates
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Homovanillic Acid