Genetic polymorphisms in juvenile-onset diabetes

Hum Hered. 1978;28(2):89-95. doi: 10.1159/000152948.

Abstract

Nine genetic polymorphic systems (ACP1, PGM1, ADA, AK, G-6-PD, Hp, ABO, Rh, MN), were studied in a series of 138 subjects affected by JOD. Differences between diabetic patients and controls were observed in the distribution of phenotypes of the red cell acid phosphatase (ACP1), and the ABO and MN blood groups.

MeSH terms

  • Acid Phosphatase / blood
  • Acid Phosphatase / genetics*
  • Blood Group Antigens*
  • Child
  • Child, Preschool
  • Diabetes Mellitus, Type 1 / genetics*
  • Erythrocytes / enzymology*
  • Female
  • Gene Frequency
  • Humans
  • Infant
  • Male
  • Phenotype
  • Polymorphism, Genetic*
  • Sex Factors

Substances

  • Blood Group Antigens
  • Acid Phosphatase