Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11

Science. 1983 Feb 4;219(4584):498-501. doi: 10.1126/science.6297001.

Abstract

The human cellular homolog of the transforming DNA sequence isolated from the bladder carcinoma cell line EJ was localized on the short arm of human chromosome 11 by Southern blot analysis of human-rodent hybrid cell DNA. This locus contains human sequences homologous to the Harvey murine sarcoma virus v-Ha-ras oncogene.

MeSH terms

  • Cell Line
  • Chromosome Mapping
  • Chromosomes, Human, 6-12 and X*
  • DNA Restriction Enzymes
  • Humans
  • Hybrid Cells
  • Nucleic Acid Hybridization
  • Oncogenes*
  • Urinary Bladder Neoplasms / genetics*

Substances

  • DNA Restriction Enzymes