A patient who had a generalized epileptiform convulsion after intra-amniotic prostaglandin F2 alpha administration with intravenous oxytocin infusion is described. The convulsion was possibly due to either or both of these drugs. The aetiological associations are reviewed. Intra-amniotic prostaglandins and intravenous oxytocin are frequently used to induce mid-trimester abortions, and the case described serves as a reminder of some of the dangers associated with this procedure.