Precipitin reaction between Sda-active human Tamm-Horsfall glycoprotein and anti-Sda-serum

Vox Sang. 1982 Mar;42(3):141-4. doi: 10.1111/j.1423-0410.1982.tb01084.x.

Abstract

Human Tamm-Horsfall glycoprotein isolated from an Sd(a+) donor, with high Sda inhibitory activity, was labelled with 14C-formaldehyde. The labelled glycoprotein was precipitated by anti-Sda sera. A good correlation was found between the precipitating and agglutinating titers of different anti-Sda sera.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigen-Antibody Reactions
  • Blood Group Antigens / immunology*
  • Carbohydrates
  • Hemagglutination Tests
  • Humans
  • Immune Sera / immunology
  • Mucoproteins / immunology*
  • Precipitins*
  • Protein Conformation
  • Uromodulin

Substances

  • Blood Group Antigens
  • Carbohydrates
  • Immune Sera
  • Mucoproteins
  • Precipitins
  • UMOD protein, human
  • Uromodulin