HLA-class II alleles in Guillain-Barré syndrome and Miller Fisher syndrome and their association with preceding Campylobacter jejuni infection

J H Rees; R W Vaughan; E Kondeatis; R A Hughes

doi:10.1016/0165-5728(95)00102-8

HLA-class II alleles in Guillain-Barré syndrome and Miller Fisher syndrome and their association with preceding Campylobacter jejuni infection

J Neuroimmunol. 1995 Oct;62(1):53-7. doi: 10.1016/0165-5728(95)00102-8.

Authors

J H Rees¹, R W Vaughan, E Kondeatis, R A Hughes

Affiliation

¹ Department of Neurology, UMDS, Guy's Hospital, London, UK.

PMID: 7499492
DOI: 10.1016/0165-5728(95)00102-8

Abstract

HLA typing for class II alleles was performed on 97 patients with Guillain-Barré syndrome or Miller Fisher syndrome and compared with 100 controls. There was a significant association between HLA-DQB1*03 and preceding Campylobacter jejuni infection (Pc = 0.05).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Campylobacter Infections / genetics*
Campylobacter Infections / immunology*
Campylobacter jejuni*
DNA / analysis
Data Interpretation, Statistical
HLA-DQ Antigens / immunology
HLA-DQ beta-Chains
Histocompatibility Antigens Class II / genetics*
Histocompatibility Antigens Class II / immunology*
Histocompatibility Testing
Humans
Polyradiculoneuropathy / genetics*
Polyradiculoneuropathy / immunology*
Polyradiculoneuropathy / microbiology
Prospective Studies

Substances

HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DQB1 antigen
Histocompatibility Antigens Class II
DNA